Has anyone tried the new migraine drug Qulipta?

[zuul]

It was just approved by the FDA in September for migraine prevention. My neurologist gave me a month’s supply of samples from the manufacturer.

The. Migraines. Just. Stopped.

After the first dose of the once-daily pill the migraines just went away. I’ve been dealing with migraines for 40 years and they just suddenly stopped.

My insurance doesn’t cover Qulipta yet, so my doctor put me in direct contact with the manufacturer and they are shipping the medication directly to my house. At no charge. If I had to pay for the drug, it would cost me about $1,000 a month.

I cannot adequately explain how life-changing this has been. I’ve been on Qulipta for about 6 weeks. No more worrying about how much water I’m drinking, or my potassium and sodium levels, or avoiding certain foods, or not getting enough sleep, or low-pressure weather systems, all of which used to be triggers for me.

The. Migraines. Just. Stopped.

On the first day that I started Qulipta, they just went away. This has been a miracle for me. The last 10 years have been utter hell. Even with Botox injections from my neurologist and once-a-month Ajovy injections, I was averaging 2 migraines a week. Before using these 2 prevention drugs, I was averaging 5 migraines a week. It was so bad that there were times that I thought about suicide. I wouldn’t describe myself as suicidal, but nobody can endure that type of pain day after day, with no hope of relief.

Qulipta changed everything for me.

[Duncanpup]

1. Fantastic

[ms liberty]

2. Marking. Thanks! n/t

[niyad]

3. That is wonderrful! I had them for many years myself, so I do certainly sympathize.

Here is to your new, migraine-free life. May it be joyous.

[zuul]

12. Thank you!

[irisblue]

4. I'm thrilled to read this is working for you

[zuul]

13. Thanks!

[ashredux]

5. SPAM

[zuul]

9. Spam? What?

I want other migraine sufferers to know that I found help. WTF are you on about?

[ashredux]

16. This is an ad....

This is ad copy designed to look like a post.

[zuul]

17. I found medication that has made a significant impact on my life

and I shared my story because I know that there are other migraine sufferers on DU. I’m hoping that others can find relief for a debilitating disease.

Do you even know what ‘ad copy’ is? Clearly you don’t.

I’m putting you on ignore since it’s obvious that you are here to disrupt while I’m sharing my story so that others might find some help. Have a nice day. Or not.

[ashredux]

18. Ignore all you want. I could care less

[Chakaconcarne]

19. It does kind of read like an ad and the bold text seems strategic

but the trials were compelling and support this kind of outcome.

Collectively it seems promising for those with migraines who have struggled to find relief.

[Escurumbele]

6. I don't know if you eat bread, ice cream, sugar stuff, drink coffee, but if you do then

stop doing all that and the migraines will go away without a prescription.

You can eat all the things you like once in a while, but not on a daily basis. I have suffered from migraines all my life, a friend told me to stop drinking coffee, I did and the migraines were less, then I got into a diet that eliminates bread completely, reduces the sugar intake by at least 90% and now they are gone, it is all natural.

Another thing I do, which may sound yacky to many people is to make myself "Garlic Tea" every morning as soon as I wake up, with REAL ORGANIC GARLIC. You need at least four teeth of garlic, placed them in a pan and boil the garlic, then I mix it with two small limes (non GMO, the ones that do have seeds), add one tea-spoon of honey to sweeten it a little bit, and drink it hot in the morning with an empty stomach.

By the way, if you can find "Key Limes", get them. They are small by they pack a lot of juice, and that is all you need.

It has lowered my blood pressure so I don't need prescription which a Dr. wanted to give me for the rest of my life.

For those of you who may say "I love garlic but I cannot eat it because it hits my stomach hard." This is the trick which I learned from a French chef:
After you peel the tooth of garlic, cut it in half along the length of the tooth, this will show a vein on each half. Take the vein out, that is where the acid that hurts your stomach is, and that is it, you can eat garlic every day (and you should, it boosts your immune system), with all kinds of food.

If you prefer the prescription and it works, then great. I just try to avoid prescriptions, but that is my preference.

[zuul]

11. I tried eliminating all of those. Didn't help.

And most of those are NOT recognized as migraine triggers.

[hlthe2b]

7. Good for you. Only migraine-sufferers appreciate how debilitating they can be.

When mine were at their peak (and I was commuting sixty miles each way for work)--I can't tell you how horrific were the episodes of having to pull over to vomit or to spend a few hours-- if I was experiencing any vertigo-- before trying again. I never had auras and thus not a lot of warning, but I could "taste" something that signaled a chemical change a few minutes before each began.

My migraines were mostly hormonal, but damn if rapid barometric pressure changes did not induce them or worsen the ones I had even more.

I'm very pleased that you are finding some relief. I now have to wonder if it will impact some of those whose long-haul COVID symptoms have included new or recurring migraine.

[zuul]

20. Thank you. Yes, I feel so bad for the long-haulers who are experiencing

migraine-like pain. On top of all the other ways that covid affects the body, the last thing any of them need is migraine.

[Farmer-Rick]

8. Wow, that's some serious medicine

It actually gets between the nerve and muscle.

Funny how everything you describe I do for just very mild headaches.I can always take Tylenol.... I'm allergic to aspirin... To stop the pain but I use it as a last resort because of the damage it can do to your liver.

My mother had migraines and they went away after she went through menopause. I'm glad I didn't inherit them. My little sister got migraines after she went through menopause, though they aren't as bad as my mother's were, and they have subsided in the last few years.

Glad you found something that works.

[zuul]

15. Both of my parents suffered with migraines and

my paternal grandmother, yet I’m the only one amongst my siblings to get them. I’m very thankful that my daughter didn’t inherit them.

[cate94]

10. I am so happy for you!

As a person who knows auras and migraines, I can’t imagine 5 a week. Holy hell. Even two a week is horrific. I am now considering myself lucky for only having 1 or 2 a month. Fortunately for me they have tapered off as I have aged. I’m glad you found relief!

[zuul]

22. I'm so glad that yours have tapered off.

During my lifetime, multiple women who are older than me told me that their migraine problems went away with menopause, or at least got better. So I was kind of looking forward to menopause.

But mine became significantly worse with the onset of menopause. Prior to that, I had a few a month. It wasn't fun but it was tolerable.

When menopause went into full swing, the migraines exploded. I keep a calendar of migraine information and during the worst period (in 2014) I experienced 87 migraines during one month. I would often get one on one side of my head, try to treat it with medication, only to have another one start on the other side of my head.

There were times during the worst period when I thought that suicide might be the answer. I was on several types of preventive and abortive migraine medications and none of it was helping. And the side effects form all the drugs! Oy!

[greymattermom]

14. That's so interesting to me

I was doing some research years ago funded by Merck on their version of the drug, telcagepant, which did not make it though phase 3 because of some liver enzyme issues. The drug worked in our research model, but Merck quit working on it. I'm glad to see that it's back. It's an oral CGRP inhibitor.

[WestMichRad]

21. One possible root cause of migraines is apparently...

…- hole in the heart. Just read an informative post about this yesterday on DailyKos. It’s worth a read!


https://www.dailykos.com/story/2022/1/19/2074772/-Ever-heard-of-a-PFO-No-Ever-get-migraines-If-so-please-read-this