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appalachiablue

(42,913 posts)
Wed Jan 29, 2020, 05:30 PM Jan 2020

Lungs Have Almost 'Magical' Ability To Repair Damage From Smoking - If You Stop; Study

BBC News, Jan. 29, 2020. Your lungs have an almost "magical" ability to repair the cancerous mutations caused by smoking - but only if you stop, say scientists.

The mutations that lead to lung cancer had been considered to be permanent, and to persist even after quitting. But the surprise findings, published in Nature, show the few cells that escape damage can repair the lungs. The effect has been seen even in patients who had smoked a pack a day for 40 years before giving up.

The thousands of chemicals in tobacco smoke corrupt and mutate the DNA in your lung cells - slowly transforming them from healthy to cancerous. The study uncovered that happening on a massive scale in a smoker's lungs even before they had cancer. The overwhelming majority of cells taken from a smoker's airways had been mutated by tobacco, with cells containing up to 10,000 genetic alterations.

"These can be thought of as mini time bombs, waiting for the next hit that causes them to progress to cancer," said Dr Kate Gowers, one of the researchers at UCL.

But a small proportion of cells went unscathed.

Exactly how they avoid the genetic devastation caused by smoking is unclear, but the researchers said they appeared to "exist in a nuclear bunker". However, after someone quits smoking, it is these cells that grow and replace the damaged cells in the lungs.

In people who quit, up to 40% of their cells looked just like those from people who had never smoked. "We were totally unprepared for the finding," Dr Peter Campbell, from the Sanger Institute, told BBC News. He added: "There is a population of cells that, kind of, magically replenish the lining of the airways. "One of the remarkable things was patients who had quit, even after 40 years of smoking, had regeneration of cells that were totally unscathed by the exposure to tobacco."...

More, https://www.bbc.com/news/health-51279355

6 replies = new reply since forum marked as read
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Lungs Have Almost 'Magical' Ability To Repair Damage From Smoking - If You Stop; Study (Original Post) appalachiablue Jan 2020 OP
sometimes its to late MFM008 Jan 2020 #1
I stopped 14 years ago - thought I'd die in my 40's. Feel great - big into cycling and working out kysrsoze Jan 2020 #2
+1 Mosby Jan 2020 #4
A couple folks we know also focused on how they weren't born appalachiablue Jan 2020 #5
9 months here - I stopped caring what Others Think alittlelark Jan 2020 #3
Bueno and take care appalachiablue Jan 2020 #6

MFM008

(20,000 posts)
1. sometimes its to late
Wed Jan 29, 2020, 05:40 PM
Jan 2020

the damage is still done to the heart or kidneys .
My dad started smoking in 1942 at age 12.
he quit 2 years before he died at 69.heart attack and kidney failure..to late.
My mom smoked 40 years and quit totally in 1995.
She still developed COPD and died last year.
I would beg, plead anyone who smokes try to stop
no matter when you started.
cigarettes always win.

kysrsoze

(6,144 posts)
2. I stopped 14 years ago - thought I'd die in my 40's. Feel great - big into cycling and working out
Wed Jan 29, 2020, 05:45 PM
Jan 2020

It's the best thing you could do for yourself, and I am so glad i quit. Smoking is an absolutely terrible thing to do to yourself. I managed to quit after I had read a book which helped me to remember there was a time where i didn't need cigarettes at all. You have to get yourself into the mindset where you picture yourself doing fine without the cigarette crutch 20x per day that you have convinced youself you can't live without. Once you get over the addiction portion, if you've got things to keep you occupied and you can remember you were just fine for years without them, it's not so difficult.

appalachiablue

(42,913 posts)
5. A couple folks we know also focused on how they weren't born
Wed Jan 29, 2020, 08:59 PM
Jan 2020

with a cigarette and quit. Good for you, cycling and exercise are great for mind and body.

https://en.wikipedia.org/wiki/Allen_Carr

alittlelark

(18,913 posts)
3. 9 months here - I stopped caring what Others Think
Wed Jan 29, 2020, 06:35 PM
Jan 2020

So sick of caring about what others think..................

Done

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