"Autophagy."

[cilla4progress]

Ring a bell with anyone here?

[MartyTheGreek]

1. Yes! Auto-Phagy self eating...

of weak cells during fasting. Multi-day water only fasts show deeper autophagy. A 5-day water only fast has shown to create Plurie Potent Stem Cells upon re-feeding. Check the work of Dr. Valter Longo at USC. Fasting Clinic True North in CA, Dr. Goldhammer. BU "Cancer as a metabolic disease". Lot's of Tubers doing crazy things with Fasting and autophagy. A Nobel prize was awarded recently for describing the process of Autophagy and how it cleans up the older and senescent cells.

[cilla4progress]

2. Cool!

My practice is far more simplified...

Husband and I started intermittent fasting when covid hit. I am doing it to get my blood glucose down - has been very effective!

My max fast is @ 20 hours. Did 19 today. I think it can be easier than people think. Has such great health bennies!!

Thanks for sharing!

[58Sunliner]

3. Lots of studies coming up through the pipeline.

MAYO study ongoing-fisetin induces autophagy and clearing of senescent cells. NMN, NR aids in autophagy, quercitin, grape seed extract also helps remove senescent cells.

[cilla4progress]

4. Thanks

for the info!

Interesting from an evolutionary perspective.

[58Sunliner]

5. You are welcome. Fisetin looks like a potential blockbuster-

It targets senescent cells in adipose tissue as well which is interesting as the body has a feedback loop with the chemicals that are released from fat.
The role of senescent cells in aging-
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214092/#:~:text=Cellular%20senescence%20is%20a%20process,%2Dsuppressor%20activation1%E2%80%936.

Preventing and Treating Neurological Disorders with the Flavonol Fisetin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7990461/

A Novel Dietary Flavonoid Fisetin Inhibits Androgen Receptor Signaling and Tumor Growth in Athymic Nude Mice
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954499/

https://www.sciencedirect.com/science/article/pii/S1347861317302116

https://www.nih.gov/news-events/nih-research-matters/fat-tissue-can-communicate-other-organs