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FSSF

(17 posts)
17. Lets see.
Tue Jan 24, 2012, 07:34 PM
Jan 2012

Keeping with the same publisher.

2010:
"In conclusion, we present evidence that an inducible response is required for efficient repair of DSBs in human fibroblasts. We suggest that this response is initiated after high doses by the radiation itself. After low doses, however, the radiation dose is insufficient to induce this response and DSB repair is inefficient. "

http://www.pnas.org/content/107/32/14205.full.pdf+html

The BEIR VII report says this:
"The committee judged that the linear no-threshold model (LNT) provided the most reasonable description of the relation between low-dose exposure to ionizing radiation and the incidence of solid cancers that are induced by ionizing radiation.
...
At doses less than 40 times the average yearly background exposure (100 mSv), statistical limitations make it difficult to evaluate cancer risk in humans. A comprehensive review of the biology data led the committee to conclude that the risk would continue in a linear fashion at lower doses without a threshold and that the smallest dose has the potential to cause a small increase in risk to humans. This assumption is termed the “linear no-threshold model” "

A recent review in Radiography covers that last part:
"Experimental research on a cellular level provides convincing evidence of a linear no-threshold relationship between dose and induction of significant DNA lesions. There is however a strong suggestion that the manner and success of the response to such damage varies with dose, cell type and individual characteristics. This apparent non-linearity does not prove absence of carcinogenic potential at low dose levels. It is the ‘no-threshold’ component of the LNT model that is of greatest significance in radiography. Regardless of whether the true shape of response is linear or non-linear, the ability of a single radiation track to cause cancer remains theoretically possible, for now. The essence of the LNT model therefore still holds, but a strict interpretation for the purposes of risk assessment and research in radiation protection no longer appears to be appropriate.

http://www.sciencedirect.com/science/article/pii/S1078817411000691

And I guess you're immune to confirmation bias then. My bad.


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